Gameweek 6 brings a pivotal opportunity to strengthen your Fantasy Premier League squad with players in form and some great fixtures ahead. From reliable defenders delivering defensive contributions to attacking midfielders and forwards showing goal threat and upside, these five picks stand out as key buys. Whether wildcarding or making strategic transfers, targeting these assets can help boost points and squad balance during this crucial phase of the season. Stay ahead of the game by adding these high potential players to your FPL team now!
Virgil Van Dijk (6.1m)
Virgil van Dijk is a top pick for the long term and a key defensive asset for Liverpool. This season, he’s averaging 12 defensive contributions per 90 minutes, which can translate into a consistent baseline of 3-4 points before a single clean sheet or bonus points are added. A clean sheet adds a guaranteed chunk of points, meaning Van Dijk can regularly offer 8+ points on good days. He’s the kind of player who’s reliable week in, week out. While not a transfer to rush into if you have no free transfers left, he should be high on the list when it’s time to wildcard, offering a solid foundation for the backline for reliable and consistent returns.
Thinking of playing your Wildcard for Gameweek 6? 🃏
One of the world’s top managers picks out a squad of 15 players for the weeks ahead 🕵️♂️
— Fantasy Premier League (@OfficialFPL) September 23, 2025
James Tarkowski (5.5m)
One player who stands out as a must have this season is James Tarkowski. Over the years, he’s proven to be a defensive powerhouse, consistently racking up defensive contributions. Already this season, Tarkowski has averaged around 12.2 defensive contributions per 90 minutes, reaching the defensive contribution points in every one of Everton games so far. Everton’s defensive solidity under David Moyes looks promising, making Tarkowski a reliable source of points week in, week out. With a great home fixture against West Ham this week, he could add attacking potential in the form of a header from a set piece alongside clean sheet and defensive contribution points. If looking for a dependable defender with both consistency and upside, Tarkowski is an option well worth targeting this gameweek.
Iliman Ndiaye (6.5m)
Everton team-mate Iliman Ndiaye has proven why so many were excited about him before the season even started. He’s returned every game except one, already registering 2 goals and 1 assist with an impressive average of nearly 11 defensive contributions per 90 minutes. Ndiaye offers strong goal and assist potential, takes penalties, and has the defensive contribution returns of a holding midfielder. Everything you’d want from a 6.5m player. At under 10% ownership, he’s a valuable differential for anyone looking to stand out. He’s definitely one to consider when planning a wildcard move, combining attacking threat with solid defensive work. Ndiaye’s all around game makes him a key asset for the middle of the season and beyond.
Phil Foden (8m)
Phil Foden remains one of the most exciting picks when fit and in form. With Manchester City facing Burnley, Brentford, and Everton in the next three games, he’s a tempting punt at just 3.5% ownership. If Pep avoids his usual rotation roulette, Foden could deliver some valuable differential points. The plan? Start him now and pivot to Cole Palmer by Gameweek 9, as Palmer’s fixtures then become highly favourable, featuring three promoted teams plus Wolves across six gameweeks. This rotation strategy offers a clever way to ride Man City’s exciting attacking options while maximising fixture potential and maintaining a differential edge in your squad. Keep an eye on Pep’s team selections, but if Foden plays, he’s an exciting gamble worth taking.
Bukayo Saka (9.8m)
Noni Madueke is now confirmed to be sidelined for the next two months with a knee injury. This opens the door for Bukayo Saka to make his long awaited return, especially after his 45-minute cameo against Manchester City. Arsenal’s fixtures start to improve from Gameweek 7 onwards, making this the perfect time to bring the English winger back into your squad. If he stays fit, Saka could be a key player as Arsenal hit a better run of form and fixtures. A smart differential pick with high upside worth considering before he becomes mainstream.
