Barnsley were also beaten in their opening outing, losing 2-1 to Notts County, so both teams will be looking to make their mark in Group D.
The Tykes are currently 10th in League One, after a 2-2 draw away at Bradford City on Saturday.
United’s U21s, meanwhile, are top of Premier League 2 with six wins out of six, and always appreciate the test against senior opposition at this level.
If the tie is as entertaining as our visit to the South Yorkshire ground in 2024, when Jack Fletcher scored twice in a dramatic 3-2 win, it will be an absorbing occasion.
